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How to Avoid Animal Testing in Your Chemical Registration

In recent years, using non-animal testing to assess chemical toxicity has become a focus of regulations such as the 2016 Toxic Substance Control Act (TSCA) reform. A significant new provision of the updated TSCA is the requirement for the U.S. EPA to release an alternative testing plan in June 2018 aimed at reducing and replacing the use of vertebrate animals in chemical testing. Methods used by the U.S. EPA's Office of Pesticide Programs and other jurisdictions worldwide to fill data gaps and estimate potential toxicity for chemicals with limited data will be covered. For those considering chemical registration in the immediate future, this session will also outline the broad regulatory landscape of chemical testing requirements and acceptance of animal testing alternatives (e.g., read-across, in vitro testing, quantitative structure-activity relationship [QSAR] models, weight-of-evidence analyses, and data waiving) when registering new industrial chemicals in the US, European Union, Canada, China, Japan, and Australia.

Presenter(s): Jiaru Zhang, Senior Toxicologist, Gradient, Catherine Willett, Director, Regulatory Toxicology, Risk Assessment and Alternatives, The Humane Society of the United States

Presentation Date: 11/4/2017

Contact Hour(s): 1.0



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